PFIZER XANAX XR is indicated for the treatment of panic disorder with or without agoraphobia, in adults. Moreover, the recommended dosage – administer PFIZER XANAX XR orally once daily, preferably in the morning. Swallow tablets whole; do not divide, crush, or chew. XANAX XR contains alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds.